Biologically Active Exosomal Components
mRNA
Supports the transfer of genetic information into target cells and plays an essential role in intercellular communication as well as the exchange of genetic signals.
miRNA
Regulates gene expression and influences central biological processes such as cell differentiation, development, and functional adaptation.
Proteins
Mediate various regulatory and communicative functions between cells and contribute to numerous regenerative and biological processes.
Discover the technology of exomed-X™
Microlyzer Blade Technology
The 600 µm Microlyzer uses specially developed micro-blades that specifically apply mechanical stress to blood cells. This controlled process leads to the release of billions of extracellular vesicles and at the same time contributes significantly to platelet activation. This precise technology creates highly effective exosome-rich plasma – the basis of Exomed-X™ therapy.
Highest vesicle density with exomed-X™
Through comprehensive device and protocol studies, Exomed-X™ achieves an exceptionally high vesicle concentration of approximately 35–40 billion vesicles per mL. With a final volume of around 5 cc, the system thus delivers an industry-leading total of 120–150 billion vesicles on average.
Exosome Criteria
For vesicles to be defined as exosomes, they must:
- be between 30–150 nm in size
- be characterized by relevant CD markers
exhibit high viability
Proven properties of exomed-X™ vesicles
Studies with Exomed-X™ show:
- Average vesicle size: 116 nm
- Percentage of platelet-derived exosomes: 98%
- Viability: 99%
These results highlight the high quality and purity of exosomes obtained with Exomed-X™.
Laboratory analytics and validated quality results
FTLA concentration and size distribution
Experiment "Striped Tube EV 1-200" (Measurements performed at Yeditepe University Biosidal and R&D Laboratories)
Flow Cytometry Results
- CD9 (platelet marker): 99.6%
- CD45 (pan-leukocyte marker): 0.3%
- CD41 (platelet GPIIb): 99.4%
- CD61 (platelet GPIIIa): 98.6%
- CD81 (TAPA-1, exosome marker): 98.5%
- 7-AAD (viability): 98.9%
Immunophenotypic analyses were performed using the Beckman Coulter DxFLEX Flow Cytometry System and analyzed with CytExpert DxFLEX. (Analysis performed in private Deren Lab.)
Particle Measurement (FTLA)
- Concentration: 40.5 × 10⁹ particles/mL
- Average Size: 116.6 nm
Independent laboratory results confirm that the Exomed-X™ Kit yields an average of 40.5 × 10⁹ vesicles per mL and an average vesicle size of 116.6 nm.
Analyses of the relevant CD markers show that 98% of the vesicles are exosomal and exhibit 99% viability.
You are interested in
exomed X™
Do you have questions about this product? We are happy to provide further information and personal consultation.
Address:
Am Hof 11/9
1010 Wien
Österreich
Email:
info@cellsup.com
Phone:
0800/700 625
Contact form
MORE PRODUCTS
Customers also bought
-
exomed IV-X™
The Exomed-X™ Kit was developed to facilitate the release of a high number of extracellular vesicles. -
exomed IV-S™
Exomed-S™ is a method for obtaining highly concentrated stem cells from autologous blood or bone marrow to activate biological repair and regeneration mechanisms in the body.
support
your
cells.
Fragen zu unseren Produkten?
Kontaktieren Sie uns, wir helfen gerne weiter!